Monthly Archives: October, 2010

Patient Power Diabetes Education

While we were developing the Corengi website this past summer, I spent some time talking with fellow Seattleite Andrew Schorr.  Andrew has been developing novel ways to communicate about healthcare online for over a decade.  These days, he’s the main man at  One of the educational tool sets they have developed at is a media player that has a comprehensive offering of information relevant to diabetes. Click on the image below to launch the player:

Player Screen Shot

Launch Press Release

Corengi Launches New Web Site to Help Type 2 Diabetes Patients Find Suitable Clinical Trials simplifies the clinical trial selection process; enables type 2 diabetes patients to make better-informed decision

Seattle, WA, Thursday, October 28 – Corengi, Inc. today announced it has launched a new web site – – to help type 2 diabetes patients find clinical trials. The free online tool asks patients a few simple questions about their condition, including weight, blood sugar, and medications among others, to help them identify which ongoing clinical trials might be right for them. According to the Center for Disease Control and Prevention, 23.6 million Americans (or 7.8 percent of the population) have diabetes, of which between 90 and 95 percent have type 2. Currently, the main online sources of type 2 diabetes clinical trial information are either incomplete, confusing, or both. With its comprehensive listing of all ongoing type 2 diabetes clinical trials in the U.S. (almost 400, 115 of which were launched since early 2010), Corengi simplifies the process of clinical trial selection for patients, and helps them quickly understand which clinical trials might be suitable.

A patient will only qualify to participate in a small percentage of these trials. Corengi gathers answers to a set of key questions needed to identify which clinical trials are appropriate for each patient and matches patients with the right clinical trial options.

“We recently surveyed 145 diabetes patients who had previously participated in a clinical trial,” explains Ryan Luce, co-founder of Corengi. “The vast majority of respondents (88 percent) indicated that they would recommend other diabetes patients to look into clinical trials. Corengi hopes to provide a simple way for type 2 diabetes patients to explore that option further.”

The American Diabetes Association endorses the multiple benefits of clinical trials: “A trial might be the only way to obtain a new cutting-edge drug or procedure, and patients on trials often receive free expert advice about taking care of their diabetes. Finally, there is the satisfaction of knowing that because of your efforts, we will better understand diabetes, and you will have contributed in a real way to making diabetes a thing of the past.” (source:

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About Corengi, Inc.

Headquartered in Seattle, WA, Corengi was founded in 2010 by healthcare industry veterans Ryan Luce and Elliot Cohen. Corengi is dedicated to helping individuals discover more about clinical trials that may be appropriate for them, and committed to building a free, comprehensive, and interactive platform for a variety of diseases. This online platform will allow stakeholders within the clinical trials community, including investigators, site personnel, sponsors, and disease advocates, to engage with potential enrollees and educate them about specific clinical trials. For more information, visit us online at

Xconomy Covers Corengi

The idea at Corengi is to help patients navigate the vast sea of clinical trials, and their arcane eligibility rules, through asking people to complete a 20-point questionnaire. If you are a newly diagnosed Type 2 diabetes patient, or know your score on a common measure of blood sugar control, this will help weed out all the potential trials that aren’t right for you. It also sifts through trials based on how close the center is to your home. Once patients have entered their questionnaire, they can get e-mail alerts when a relevant trial opens up in their area.

Full story here

CDC Projects Doubling of Diabetes Incidence by 2050

New report from the Centers for Disease Control and Prevention:

As many as 1 in 3 U.S. adults could have diabetes by 2050 if current trends continue, according to a new analysis from the Centers for Disease Control and Prevention.

One in 10 U.S. adults has diabetes now. The prevalence is expected to rise sharply over the next 40 years due to an aging population more likely to develop type 2 diabetes, increases in minority groups that are at high risk for type 2 diabetes, and people with diabetes living longer, according to CDC projections published in the journal Population Health Metrics. Because the study factored in aging, minority populations and lifespan, the projections are higher than previous estimates.

Hypothetical Patient Trial Matching

I wanted to give an example of how Corengi can help you narrow down to clinically appropriate clinical trials.  Lets imagine a type 2 diabetes patient who is interested in finding a clinical trial.  She lives in the United States – so she does an advanced search for open trials in the U.S. on for type 2 diabetes.

She finds 309 open studies.  Wow – that’s a lot.  But wait, our hypothetical patient happens to be taking insulin.  She wants to narrow down the studies to those who need the patient to be on insulin.  She uses the advanced search and enters “insulin” as a key term:

She’s narrowed it down to 138 trials.  Helpful, right?  Unfortunately, the answer is “no”.  Looking at those trials, for at least 30 of them, you can’t be on insulin to enter the trial.  The search is looking at “insulin” as a key term, not as a requirement for entry.

Next, our hypothetical patient creates an account on Corengi,  She indicates that she is taking insulin (and not taking metformin), narrowing down the list to 195 potential trials – we’ve found a lot more trials where she may be qualified!

Additionally, our hypothetical patient indicates that she is 50 years old, was diagnosed in October 2009, weighs 150 pounds, is 5’4”, and has an HbA1c of 7.5%.

Using this information, the Corengi matching engine now shows 119 trials that may be appropriate.  Using the options page, she can quickly identify which of these have additional restrictive criteria – and sees that there are 7 trials within a 30 mile radius of where she lives.  (Our hypothetical patient lives in Seattle, WA – like me.  We happen to be good friends…)

Participants Recommend Trials to Others

We recently surveyed diabetes patients to find out more about what they thought about clinical trials.  Among patients who had actually participated in a clinical trial in the past (145 respondents), we asked the following question:

Would you recommend other diabetes patients look into participating in a clinical trial?

Yes, I would recommend other patients look into clinical trials     88%

No, I would not recommend other patients look into clinical trials       0%

Not sure      12%

That’s right – among diabetes patients who participated in a trial, none of them said “No, I would not recommend other patients looks into clinical trials.”  Only 12% said “Not sure”.  The rest of the patients (almost 90% of them) said they would recommend the trial.

Welcome to Corengi

Welcome to!  Our goal is help patients understand what clinical trials are right for them, what those trials mean, and what it will be like to participate.

My name is Ryan Luce and I left my job as Director of Product Development at NexCura to start Corengi earlier this year.   A team of first rate developers, lead by out Chief Technical Officer Elliot Cohen, has been working round the clock to get this new website launched.

Corengi is a matching engine, allowing type 2 diabetes patients to identify clinical trials for which they may be qualified.

Our goal is to improve!  Tell us what you need on this site to learn more about clinical trials!   Email us directly at and let us know what works and what doesn’t.